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Protective CD4(+) Th1 cell-mediated immunity is reliant upon execution of effector function prior to the establishment of the pathogen niche
Intracellular infection with the parasite Leishmania major features a state of concomitant immunity in which CD4(+) T helper 1 (Th1) cell-mediated immunity against reinfection coincides with a chronic but sub-clinical primary infection. In this setting, the rapidity of the Th1 response at a secondar...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8483310/ https://www.ncbi.nlm.nih.gov/pubmed/34543348 http://dx.doi.org/10.1371/journal.ppat.1009944 |