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Androgen receptor transactivates KSHV noncoding RNA PAN to promote lytic replication–mediated oncogenesis: A mechanism of sex disparity in KS

Kaposi’s sarcoma-associated herpesvirus (KSHV) preferentially infects and causes Kaposi’s sarcoma (KS) in male patients. However, the biological mechanisms are largely unknown. This study was novel in confirming the extensive nuclear distribution of the androgen receptor (AR) and its co-localization...

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Detalles Bibliográficos
Autores principales: Ding, Mingzhu, Wu, Jinfeng, Sun, Rui, Yan, Lijun, Bai, Lei, Shi, Jiajian, Feng, Hua, Zhang, Yuqi, Lan, Ke, Wang, Xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8483343/
https://www.ncbi.nlm.nih.gov/pubmed/34543357
http://dx.doi.org/10.1371/journal.ppat.1009947