Cargando…
Androgen receptor transactivates KSHV noncoding RNA PAN to promote lytic replication–mediated oncogenesis: A mechanism of sex disparity in KS
Kaposi’s sarcoma-associated herpesvirus (KSHV) preferentially infects and causes Kaposi’s sarcoma (KS) in male patients. However, the biological mechanisms are largely unknown. This study was novel in confirming the extensive nuclear distribution of the androgen receptor (AR) and its co-localization...
Autores principales: | Ding, Mingzhu, Wu, Jinfeng, Sun, Rui, Yan, Lijun, Bai, Lei, Shi, Jiajian, Feng, Hua, Zhang, Yuqi, Lan, Ke, Wang, Xing |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8483343/ https://www.ncbi.nlm.nih.gov/pubmed/34543357 http://dx.doi.org/10.1371/journal.ppat.1009947 |
Ejemplares similares
-
K13 Blocks KSHV Lytic Replication and Deregulates vIL6 and hIL6 Expression: A Model of Lytic Replication Induced Clonal Selection in Viral Oncogenesis
por: Zhao, Jinshun, et al.
Publicado: (2007) -
RSK1 SUMOylation is required for KSHV lytic replication
por: Liu, Zhenshan, et al.
Publicado: (2021) -
KSHV Targeted Therapy: An Update on Inhibitors of Viral Lytic Replication
por: Coen, Natacha, et al.
Publicado: (2014) -
Activation of DNA Damage Response Pathways during Lytic Replication of KSHV
por: Hollingworth, Robert, et al.
Publicado: (2015) -
The Kaposi sarcoma-associated herpesvirus (KSHV) is present as an intact latent genome in KS tissue but replicates in the peripheral blood mononuclear cells of KS patients
Publicado: (1996)