The critical balance between dopamine D2 receptor and RGS for the sensitive detection of a transient decay in dopamine signal

In behavioral learning, reward-related events are encoded into phasic dopamine (DA) signals in the brain. In particular, unexpected reward omission leads to a phasic decrease in DA (DA dip) in the striatum, which triggers long-term potentiation (LTP) in DA D2 receptor (D2R)-expressing spiny-projecti...

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Detalles Bibliográficos
Autores principales: Urakubo, Hidetoshi, Yagishita, Sho, Kasai, Haruo, Kubota, Yoshiyuki, Ishii, Shin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8483376/
https://www.ncbi.nlm.nih.gov/pubmed/34591840
http://dx.doi.org/10.1371/journal.pcbi.1009364

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8483376/
https://www.ncbi.nlm.nih.gov/pubmed/34591840
http://dx.doi.org/10.1371/journal.pcbi.1009364

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