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The critical balance between dopamine D2 receptor and RGS for the sensitive detection of a transient decay in dopamine signal
In behavioral learning, reward-related events are encoded into phasic dopamine (DA) signals in the brain. In particular, unexpected reward omission leads to a phasic decrease in DA (DA dip) in the striatum, which triggers long-term potentiation (LTP) in DA D2 receptor (D2R)-expressing spiny-projecti...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8483376/ https://www.ncbi.nlm.nih.gov/pubmed/34591840 http://dx.doi.org/10.1371/journal.pcbi.1009364 |