Short and Modular Synthesis of Substituted 2-Aminopyrroles

[Image: see text] We herein describe a simple and metal-free domino methodology to synthesize 2-aminopyrroles from alkynyl vinyl hydrazides. The domino reaction involves a novel propargylic 3,4-diaza-Cope rearrangement and a tandem isomerization/5-exo-dig N-cyclization reaction. By using this approa...

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Detalles Bibliográficos
Autores principales: Diana-Rivero, Raquel, Halsvik, Beate, García Tellado, Fernando, Tejedor, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8483442/
https://www.ncbi.nlm.nih.gov/pubmed/33929868
http://dx.doi.org/10.1021/acs.orglett.1c01345

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8483442/
https://www.ncbi.nlm.nih.gov/pubmed/33929868
http://dx.doi.org/10.1021/acs.orglett.1c01345

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