Endothelial Spns2 and ApoM Regulation of Vascular Tone and Hypertension Via Sphingosine‐1‐Phosphate

BACKGROUND: Most of the circulating sphingosine‐1‐phosphate (S1P) is bound to ApoM (apolipoprotein M) of high‐density lipoprotein (HDL) and mediates many beneficial effects of HDL on the vasculature via G protein–coupled S1P receptors. HDL‐bound S1P is decreased in atherosclerosis, myocardial infarc...

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Detalles Bibliográficos
Autores principales: Del Gaudio, Ilaria, Rubinelli, Luisa, Sasset, Linda, Wadsack, Christian, Hla, Timothy, Di Lorenzo, Annarita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8483458/
https://www.ncbi.nlm.nih.gov/pubmed/34240614
http://dx.doi.org/10.1161/JAHA.121.021261

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8483458/
https://www.ncbi.nlm.nih.gov/pubmed/34240614
http://dx.doi.org/10.1161/JAHA.121.021261

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