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Irradiation Accelerates Plaque Formation and Cellular Senescence in Flow‐Altered Carotid Arteries of Apolipoprotein E Knock‐Out Mice

BACKGROUND: Chronic inflammation through cellular senescence, known as the senescence‐associated secretory phenotype, is a mechanism of various organ diseases, including atherosclerosis. Particularly, ionizing radiation (IR) contributes to cellular senescence by causing DNA damage. Although previous...

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Detalles Bibliográficos
Autores principales: Yamamoto, Yu, Minami, Manabu, Yoshida, Kazumichi, Nagata, Manabu, Miyata, Takeshi, Yang, Tao, Takayama, Naoki, Suzuki, Keita, Okawa, Masakazu, Yamada, Kiyofumi, Miyamoto, Susumu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8483483/
https://www.ncbi.nlm.nih.gov/pubmed/34227406
http://dx.doi.org/10.1161/JAHA.120.020712