Cellular Mechanisms Underlying the Low Cardiotoxicity of Istaroxime

BACKGROUND: Istaroxime is an inhibitor of Na(+)/K(+) ATPase with proven efficacy to increase cardiac contractility and to accelerate relaxation attributable to a relief in phospholamban‐dependent inhibition of the sarcoplasmic reticulum Ca(2+) ATPase. We have previously shown that pharmacologic Na(+...

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Detalles Bibliográficos
Autores principales: Racioppi, María Florencia, Burgos, Juan Ignacio, Morell, Malena, Gonano, Luis Alberto, Vila Petroff, Martín
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8483492/
https://www.ncbi.nlm.nih.gov/pubmed/34219467
http://dx.doi.org/10.1161/JAHA.120.018833

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8483492/
https://www.ncbi.nlm.nih.gov/pubmed/34219467
http://dx.doi.org/10.1161/JAHA.120.018833

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