Modulation of Sirt1 and FoxO1 on Hypothalamic Leptin‐Mediated Sympathetic Activation and Inflammation in Diet‐Induced Obese Rats

BACKGROUND: Hypothalamic leptin‐mediated signaling contributes to the exaggerated sympatho‐excitation and increased blood pressure in obesity‐associated hypertension. The aim of the study was to investigate the roles of energy‐sensing enzyme sirtuin1 (Sirt1) and forkhead box protein O1 (FoxO1) on th...

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Detalles Bibliográficos
Autores principales: Liu, Xuefei, Zheng, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8483493/
https://www.ncbi.nlm.nih.gov/pubmed/34259031
http://dx.doi.org/10.1161/JAHA.120.020667

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8483493/
https://www.ncbi.nlm.nih.gov/pubmed/34259031
http://dx.doi.org/10.1161/JAHA.120.020667

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