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Nonproductive Splicing Prevents Expression of MYH7b Protein in the Mammalian Heart

BACKGROUND: Although the roles of alpha‐myosin heavy chain (α‐MyHC) and beta‐myosin heavy chain (β‐MyHC) proteins in cardiac contractility have long been appreciated, the biological contribution of another closely related sarcomeric myosin family member, MYH7b (myosin heavy chain 7b), has become a m...

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Detalles Bibliográficos
Autores principales: Lee, Lindsey A., Broadwell, Lindsey J., Buvoli, Massimo, Leinwand, Leslie A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8483497/
https://www.ncbi.nlm.nih.gov/pubmed/34227390
http://dx.doi.org/10.1161/JAHA.121.020965