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Circulating Mature PCSK9 Level Predicts Diminished Response to Statin Therapy

BACKGROUND: Statin‐mediated efficacy of lowering low‐density lipoprotein (LDL) cholesterol varies in each individual, and its diminished response is associated with worse outcomes. However, there is no established approach to predict hyporesponse to statins. PCSK9 (proprotein convertase subxilisin/k...

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Detalles Bibliográficos
Autores principales: Kuyama, Naoto, Kataoka, Yu, Takegami, Misa, Nishimura, Kunihiro, Harada‐Shiba, Mariko, Hori, Mika, Ogura, Masatsune, Otsuka, Fumiyuki, Asaumi, Yasuhide, Noguchi, Teruo, Tsujita, Kenichi, Yasuda, Satoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8483520/
https://www.ncbi.nlm.nih.gov/pubmed/33998287
http://dx.doi.org/10.1161/JAHA.120.019525