COL5A1 Variants Cause Aortic Dissection by Activating TGF‐β‐Signaling Pathway

BACKGROUND: Aortic dissection (AD) is one of the most life‐threatening cardiovascular diseases that exhibit high genetic heterogeneity. However, it is unclear whether variants within the COL5A1 gene can cause AD. Therefore, we intend to determine whether COL5A1 is a causative gene of AD. METHODS AND...

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Detalles Bibliográficos
Autores principales: Chen, Peng, Yu, Bo, Li, Zongzhe, Chen, Yanghui, Sun, Yang, Wang, Dao Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8483548/
https://www.ncbi.nlm.nih.gov/pubmed/34041919
http://dx.doi.org/10.1161/JAHA.120.019276

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8483548/
https://www.ncbi.nlm.nih.gov/pubmed/34041919
http://dx.doi.org/10.1161/JAHA.120.019276

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