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PAK1 Silencing Attenuated Proinflammatory Macrophage Activation and Foam Cell Formation by Increasing PPARγ Expression

Macrophage polarization in response to environmental cues has emerged as an important event in the development of atherosclerosis. Compelling evidences suggest that P21-activated kinases 1 (PAK1) is involved in a wide variety of diseases. However, the potential role and mechanism of PAK1 in regulati...

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Detalles Bibliográficos
Autores principales: Cheng, Wen-Lin, Zhang, Quan, Li, Bo, Cao, Jian-Lei, Jiao, Lin, Chao, Sheng-Ping, Lu, Zhibing, Zhao, Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8483905/
https://www.ncbi.nlm.nih.gov/pubmed/34603600
http://dx.doi.org/10.1155/2021/6957900