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A Computational Framework to Identify Transcriptional and Network Differences between Hepatocellular Carcinoma and Normal Liver Tissue and Their Applications in Repositioning Drugs

Hepatocellular carcinoma (HCC) is one of the most common and lethal malignancies worldwide. Although there have been extensive studies on the molecular mechanisms of its carcinogenesis, FDA-approved drugs for HCC are rare. Side effects, development time, and cost of these drugs are the major bottlen...

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Detalles Bibliográficos
Autores principales: Hu, Aimin, Wei, Zheng, Zheng, Zuxiang, Luo, Bichao, Yi, Jieming, Zhou, Xinhong, Zeng, Changjiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8483911/
https://www.ncbi.nlm.nih.gov/pubmed/34604388
http://dx.doi.org/10.1155/2021/9921195