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Insights in ChAdOx1 nCoV-19 vaccine-induced immune thrombotic thrombocytopenia

SARS-CoV-2 vaccine ChAdOx1 nCoV-19 (AstraZeneca) causes a thromboembolic complication termed vaccine-induced immune thrombotic thrombocytopenia (VITT). Using biophysical techniques, mouse models, and analysis of VITT patient samples, we identified determinants of this vaccine-induced adverse reactio...

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Detalles Bibliográficos
Autores principales: Greinacher, Andreas, Selleng, Kathleen, Palankar, Raghavendra, Wesche, Jan, Handtke, Stefan, Wolff, Martina, Aurich, Konstanze, Lalk, Michael, Methling, Karen, Völker, Uwe, Hentschker, Christian, Michalik, Stephan, Steil, Leif, Reder, Alexander, Schönborn, Linda, Beer, Martin, Franzke, Kati, Büttner, Andreas, Fehse, Boris, Stavrou, Evi X., Rangaswamy, Chandini, Mailer, Reiner K., Englert, Hanna, Frye, Maike, Thiele, Thomas, Kochanek, Stefan, Krutzke, Lea, Siegerist, Florian, Endlich, Nicole, Warkentin, Theodore E., Renné, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8483989/
https://www.ncbi.nlm.nih.gov/pubmed/34587242
http://dx.doi.org/10.1182/blood.2021013231