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Influence of lactide vs glycolide composition of poly (lactic-co-glycolic acid) polymers on encapsulation of hydrophobic molecules: molecular dynamics and formulation studies

The work demonstrates the preparation of PLGA (PLGA 50:50, PLGA 75:25) nanoparticles, to encapsulate a hydrophobic molecule (coumarin-6), using the microreactor-based continuous process. The formulations were characterized using dynamic light scattering and transmission electron microscopy to determ...

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Detalles Bibliográficos
Autores principales: Dobhal, Anurag, Srivastav, Ashu, Dandekar, Prajakta, Jain, Ratnesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8484083/
https://www.ncbi.nlm.nih.gov/pubmed/34591178
http://dx.doi.org/10.1007/s10856-021-06580-0