A phase 1, open-label, drug–drug interaction study of rucaparib with rosuvastatin and oral contraceptives in patients with advanced solid tumors

PURPOSE: This study aimed at evaluating the effect of rucaparib on the pharmacokinetics of rosuvastatin and oral contraceptives in patients with advanced solid tumors and the safety of rucaparib with and without coadministration of rosuvastatin or oral contraceptives. METHODS: Patients received sing...

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Detalles Bibliográficos
Autores principales: Liao, Mingxiang, Jeziorski, Krzysztof G., Tomaszewska-Kiecana, Monika, Láng, István, Jasiówka, Marek, Skarbová, Viera, Centkowski, Piotr, Ramlau, Rodryg, Górnaś, Maria, Lee, John, Edwards, Sarah, Habeck, Jenn, Nash, Eileen, Grechko, Nikolay, Xiao, Jim J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8484168/
https://www.ncbi.nlm.nih.gov/pubmed/34370076
http://dx.doi.org/10.1007/s00280-021-04338-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8484168/
https://www.ncbi.nlm.nih.gov/pubmed/34370076
http://dx.doi.org/10.1007/s00280-021-04338-7

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