Suppression of autophagy promotes fibroblast activation in p53-deficient colorectal cancer cells

Deficiency of p53 in cancer cells activates the transformation of normal tissue fibroblasts into carcinoma-associated fibroblasts; this promotes tumor progression through a variety of mechanisms in the tumor microenvironment. The role of autophagy in carcinoma-associated fibroblasts in tumor progres...

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Detalles Bibliográficos
Autores principales: Inoue, Takanori, Hayashi, Yoshito, Tsujii, Yoshiki, Yoshii, Shunsuke, Sakatani, Akihiko, Kimura, Keiichi, Uema, Ryotaro, Kato, Minoru, Saiki, Hirotsugu, Shinzaki, Shinichiro, Iijima, Hideki, Takehara, Tetsuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8484348/
https://www.ncbi.nlm.nih.gov/pubmed/34593902
http://dx.doi.org/10.1038/s41598-021-98865-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8484348/
https://www.ncbi.nlm.nih.gov/pubmed/34593902
http://dx.doi.org/10.1038/s41598-021-98865-1

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