Performance of a scalable RNA extraction-free transcriptome profiling method for adherent cultured human cells

RNA sequencing enables high-content/high-complexity measurements in small molecule screens. Whereas the costs of DNA sequencing and RNA-seq library preparation have decreased consistently, RNA extraction remains a significant bottleneck to scalability. We evaluate the performance of a bulk RNA-seq l...

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Detalles Bibliográficos
Autores principales: Ghimire, Shreya, Stewart, Carley G., Thurman, Andrew L., Pezzulo, Alejandro A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8484438/
https://www.ncbi.nlm.nih.gov/pubmed/34593905
http://dx.doi.org/10.1038/s41598-021-98912-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8484438/
https://www.ncbi.nlm.nih.gov/pubmed/34593905
http://dx.doi.org/10.1038/s41598-021-98912-x

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