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ECNet is an evolutionary context-integrated deep learning framework for protein engineering

Machine learning has been increasingly used for protein engineering. However, because the general sequence contexts they capture are not specific to the protein being engineered, the accuracy of existing machine learning algorithms is rather limited. Here, we report ECNet (evolutionary context-integ...

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Detalles Bibliográficos
Autores principales: Luo, Yunan, Jiang, Guangde, Yu, Tianhao, Liu, Yang, Vo, Lam, Ding, Hantian, Su, Yufeng, Qian, Wesley Wei, Zhao, Huimin, Peng, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8484459/
https://www.ncbi.nlm.nih.gov/pubmed/34593817
http://dx.doi.org/10.1038/s41467-021-25976-8