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Targeting the CD146/Galectin-9 axis protects the integrity of the blood–brain barrier in experimental cerebral malaria

Cerebral malaria (CM) is a life-threatening diffuse encephalopathy caused by Plasmodium falciparum, in which the destruction of the blood–brain barrier (BBB) is the main cause of death. However, increasing evidence has shown that antimalarial drugs, the current treatment for CM, do little to protect...

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Detalles Bibliográficos
Autores principales: Duan, Hongxia, Zhao, Shuai, Xiang, Jianquan, Ju, Chenhui, Chen, Xuehui, Gramaglia, Irene, Yan, Xiyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8484550/
https://www.ncbi.nlm.nih.gov/pubmed/33203936
http://dx.doi.org/10.1038/s41423-020-00582-8