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Time of Day-Dependent Alterations in Hippocampal Kynurenic Acid, Glutamate, and GABA in Adult Rats Exposed to Elevated Kynurenic Acid During Neurodevelopment

Hypofunction of glutamatergic signaling is causally linked to neurodevelopmental disorders, including psychotic disorders like schizophrenia and bipolar disorder. Kynurenic acid (KYNA) has been found to be elevated in postmortem brain tissue and cerebrospinal fluid of patients with psychotic illness...

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Detalles Bibliográficos
Autores principales: Wright, Courtney J., Rentschler, Katherine M., Wagner, Nathan T. J., Lewis, Ashley M., Beggiato, Sarah, Pocivavsek, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8484637/
https://www.ncbi.nlm.nih.gov/pubmed/34603109
http://dx.doi.org/10.3389/fpsyt.2021.734984