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Wdr1 and cofilin are necessary mediators of immune-cell-specific apoptosis triggered by Tecfidera

Despite the emerging importance of reactive electrophilic drugs, deconvolution of their principal targets remains difficult. The lack of genetic tractability/interventions and reliance on secondary validation using other non-specific compounds frequently complicate the earmarking of individual binde...

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Detalles Bibliográficos
Autores principales: Poganik, Jesse R., Huang, Kuan-Ting, Parvez, Saba, Zhao, Yi, Raja, Sruthi, Long, Marcus J. C., Aye, Yimon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8484674/
https://www.ncbi.nlm.nih.gov/pubmed/34593792
http://dx.doi.org/10.1038/s41467-021-25466-x