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Co-targeting TGF-β and PD-L1 with radiation therapy: The Goldilocks principle

In the current issue of Cancer Cell, Lan et al.(1) demonstrate that a bifunctional fusion protein targeting TGF-β and PD-L1 can synergize with radiation therapy to simultaneously augment tumor control and reduce normal tissue toxicity.

Detalles Bibliográficos
Autores principales: Bakhoum, Samuel F., Rudin, Charles M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8484681/
https://www.ncbi.nlm.nih.gov/pubmed/34622240
http://dx.doi.org/10.1016/j.xcrm.2021.100406