The Chloride Homeostasis of CA3 Hippocampal Neurons Is Not Altered in Fully Symptomatic Mepc2-null Mice

Rett syndrome (RTT) is an X-linked neurodevelopmental disorder caused mainly by mutations in the MECP2 gene. Mouse models of RTT show reduced expression of the cation-chloride cotransporter KCC2 and altered chloride homeostasis at presymptomatic stages. However, whether these alterations persist to...

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Detalles Bibliográficos
Autores principales: Belaïdouni, Yasmine, Diabira, Diabe, Zhang, Jinwei, Graziano, Jean-Charles, Bader, Francesca, Montheil, Aurelie, Menuet, Clément, Wayman, Gary A., Gaiarsa, Jean-Luc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8484709/
https://www.ncbi.nlm.nih.gov/pubmed/34602980
http://dx.doi.org/10.3389/fncel.2021.724976

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8484709/
https://www.ncbi.nlm.nih.gov/pubmed/34602980
http://dx.doi.org/10.3389/fncel.2021.724976

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