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Structural delineation and phase-dependent activation of the costimulatory CD27:CD70 complex

CD27 is a tumor necrosis factor (TNF) receptor, which stimulates lymphocytes and promotes their differentiation upon activation by TNF ligand CD70. Activation of the CD27 receptor provides a costimulatory signal to promote T cell, B cell, and NK cell activity to facilitate antitumor and anti-infecti...

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Detalles Bibliográficos
Autores principales: Liu, Weifeng, Maben, Zachary, Wang, Carole, Lindquist, Kevin C., Li, Manqing, Rayannavar, Vinayak, Lopez Armenta, Ilsel, Nager, Andrew, Pascua, Edward, Dominik, Pawel K., Oyen, David, Wang, Hui, Roach, Rachel Carson, Allan, Corey M., Mosyak, Lidia, Chaparro-Riggers, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8484739/
https://www.ncbi.nlm.nih.gov/pubmed/34419446
http://dx.doi.org/10.1016/j.jbc.2021.101102