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Successful Treatment of Advanced Intrahepatic Cholangiocarcinoma With a High Tumor Mutational Burden and PD-L1 Expression by PD-1 Blockade Combined With Tyrosine Kinase Inhibitors: A Case Report

Advanced intrahepatic cholangiocarcinoma (iCCA) is not suitable for surgical treatment. Guided by the concept of precision medicine, preoperative systematic treatment may reshape the clinical outcomes of advanced intrahepatic cholangiocarcinoma patients. We describe the case of a 38-year-old female...

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Detalles Bibliográficos
Autores principales: Zhang, Ze, Zhang, Wenwen, Wang, Hongguang, Hu, Bingyang, Wang, Zhanbo, Lu, Shichun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8484748/
https://www.ncbi.nlm.nih.gov/pubmed/34603331
http://dx.doi.org/10.3389/fimmu.2021.744571