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Emerging Place of JAK Inhibitors in the Treatment of Inborn Errors of Immunity

Among inborn errors of immunity (IEIs), some conditions are characterized by inflammation and autoimmunity at the front line and are particularly challenging to treat. Monogenic diseases associated with gain-of-function mutations in genes critical for cytokine signaling through the JAK-STAT pathway...

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Detalles Bibliográficos
Autores principales: Hadjadj, Jérôme, Frémond, Marie-Louise, Neven, Bénédicte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8484879/
https://www.ncbi.nlm.nih.gov/pubmed/34603291
http://dx.doi.org/10.3389/fimmu.2021.717388