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Recent Advances in Repurposing Disulfiram and Disulfiram Derivatives as Copper-Dependent Anticancer Agents

Copper (Cu) plays a pivotal role in cancer progression by acting as a co-factor that regulates the activity of many enzymes and structural proteins in cancer cells. Therefore, Cu-based complexes have been investigated as novel anticancer metallodrugs and are considered as a complementary strategy fo...

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Detalles Bibliográficos
Autores principales: Kannappan, Vinodh, Ali, Misha, Small, Benjamin, Rajendran, Gowtham, Elzhenni, Salena, Taj, Hamza, Wang, Weiguang, Dou, Q. Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8484884/
https://www.ncbi.nlm.nih.gov/pubmed/34604310
http://dx.doi.org/10.3389/fmolb.2021.741316