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Recent Advances in Repurposing Disulfiram and Disulfiram Derivatives as Copper-Dependent Anticancer Agents
Copper (Cu) plays a pivotal role in cancer progression by acting as a co-factor that regulates the activity of many enzymes and structural proteins in cancer cells. Therefore, Cu-based complexes have been investigated as novel anticancer metallodrugs and are considered as a complementary strategy fo...
Autores principales: | Kannappan, Vinodh, Ali, Misha, Small, Benjamin, Rajendran, Gowtham, Elzhenni, Salena, Taj, Hamza, Wang, Weiguang, Dou, Q. Ping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8484884/ https://www.ncbi.nlm.nih.gov/pubmed/34604310 http://dx.doi.org/10.3389/fmolb.2021.741316 |
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