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Single Immunization of a Vaccine Vectored by a Novel Recombinant Vaccinia Virus Affords Effective Protection Against Respiratory Syncytial Virus Infection in Cotton Rats

Respiratory syncytial virus (RSV) is a leading cause of respiratory infections worldwide and disease management measures are hampered by the lack of a safe and effective vaccine against the infection. We constructed a novel recombinant RSV vaccine candidate based on a deletion mutant vaccinia virus...

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Detalles Bibliográficos
Autores principales: Russell, Marsha S., Thulasi Raman, Sathya N., Gravel, Caroline, Zhang, Wanyue, Pfeifle, Annabelle, Chen, Wangxue, Van Domselaar, Gary, Safronetz, David, Johnston, Michael, Sauve, Simon, Wang, Lisheng, Rosu-Myles, Michael, Cao, Jingxin, Li, Xuguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8484905/
https://www.ncbi.nlm.nih.gov/pubmed/34603336
http://dx.doi.org/10.3389/fimmu.2021.747866