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CRISPR-Based Activation of Endogenous Expression of TPM1 Inhibits Inflammatory Response of Primary Human Coronary Artery Endothelial and Smooth Muscle Cells Induced by Recombinant Human Tumor Necrosis Factor α

Tumor necrosis factor α (TNFα) is one of the most important proinflammatory cytokines, which affects many processes associated with the growth and characteristics of endothelial, smooth muscle, and immune system cells. However, there is no correlation between most in vivo and in vitro studies on its...

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Detalles Bibliográficos
Autores principales: Gagat, Maciej, Zielińska, Wioletta, Mikołajczyk, Klaudia, Zabrzyński, Jan, Krajewski, Adrian, Klimaszewska-Wiśniewska, Anna, Grzanka, Dariusz, Grzanka, Alina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8484921/
https://www.ncbi.nlm.nih.gov/pubmed/34604206
http://dx.doi.org/10.3389/fcell.2021.668032