Karnovsky’s fixative prevents artifacts appearing as vacuolation derived from tissue processing in kidneys treated with antisense oligonucleotide

Antisense oligonucleotide (ASO) therapies have been identified as a new treatment modality for intractable diseases. In kidneys treated with ASOs, vacuoles, in addition to basophilic granules, are often observed in the proximal tubules. Some reports have described that these vacuoles are likely to b...

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Detalles Bibliográficos
Autores principales: Nishina, Hironobu, Sakairi, Tetsuya, Kashimura, Akane, Sato, Hiroko, Mizukawa, Mao, Ozawa, Yuhei, Nishikawa, Satomi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society of Toxicologic Pathology 2021
Materias:
Technical Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8484925/
https://www.ncbi.nlm.nih.gov/pubmed/34629736
http://dx.doi.org/10.1293/tox.2021-0007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8484925/
https://www.ncbi.nlm.nih.gov/pubmed/34629736
http://dx.doi.org/10.1293/tox.2021-0007

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