Time-course changes in 5-fluorouracil-induced neural progenitor cell damages in the developing rat brain

5-Fluorouracil (5-Fu) is a DNA-damaging agent and teratogenic in rodents. This study aimed to investigate its influence on neural progenitor cells (NPCs) in the developing fetal rat brain. Dams were intraperitoneally injected with 5-Fu (50 mg/kg b.w.) on gestation day 13 and its effects on fetal NPC...

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Detalles Bibliográficos
Autores principales: Yamaguchi, Yuko, Fukunaga, Yachiyo, Takagi, Mizuho, Saito, Tsubasa, Tamura, Kazutoshi, Hoshiya, Toru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society of Toxicologic Pathology 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8484929/
https://www.ncbi.nlm.nih.gov/pubmed/34621107
http://dx.doi.org/10.1293/tox.2020-0070

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8484929/
https://www.ncbi.nlm.nih.gov/pubmed/34621107
http://dx.doi.org/10.1293/tox.2020-0070

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