The Off-Targets of Clustered Regularly Interspaced Short Palindromic Repeats Gene Editing

The repurposing of the CRISPR/Cas bacterial defense system against bacteriophages as simple and flexible molecular tools has revolutionized the field of gene editing. These tools are now widely used in basic research and clinical trials involving human somatic cells. However, a global moratorium on...

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Detalles Bibliográficos
Autores principales: Vicente, Manuel M., Chaves-Ferreira, Miguel, Jorge, João M. P., Proença, João T., Barreto, Vasco M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8484971/
https://www.ncbi.nlm.nih.gov/pubmed/34604217
http://dx.doi.org/10.3389/fcell.2021.718466

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8484971/
https://www.ncbi.nlm.nih.gov/pubmed/34604217
http://dx.doi.org/10.3389/fcell.2021.718466

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