Dihydroartemisinin triggers ferroptosis in primary liver cancer cells by promoting and unfolded protein response-induced upregulation of CHAC1 expression

Dihydroartemisinin (DHA), an artemisinin derivate, has been investigated as a potential antitumor drug in primary liver cancer (PLC). Ferroptosis is a form of iron-dependent cell death that can be driven by lipid peroxidation inducers. The present study aimed to determine whether and how DHA could p...

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Detalles Bibliográficos
Autores principales: Wang, Zhiwei, Li, Mingxing, Liu, Yuanfeng, Qiao, Zhentao, Bai, Tao, Yang, Ling, Liu, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8485000/
https://www.ncbi.nlm.nih.gov/pubmed/34558645
http://dx.doi.org/10.3892/or.2021.8191

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8485000/
https://www.ncbi.nlm.nih.gov/pubmed/34558645
http://dx.doi.org/10.3892/or.2021.8191

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