Attrition of methylnaltrexone treatment-emergent adverse events in patients with chronic noncancer pain and opioid-induced constipation: a post hoc pooled analysis of two clinical trials

Background: Opioids prescribed for the management of chronic noncancer pain are associated with nausea, vomiting, and constipation. Methylnaltrexone, a peripherally acting µ-opioid receptor antagonist, has demonstrated robust efficacy and was well-tolerated in treating opioid-induced constipation wi...

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Detalles Bibliográficos
Autores principales: Mehta, Neel, Slatkin, Neal E., Israel, Robert J., Stambler, Nancy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8485099/
https://www.ncbi.nlm.nih.gov/pubmed/34631030
http://dx.doi.org/10.12688/f1000research.51073.2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8485099/
https://www.ncbi.nlm.nih.gov/pubmed/34631030
http://dx.doi.org/10.12688/f1000research.51073.2

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