Cargando…

PPARγ attenuates hepatic inflammation and oxidative stress of non-alcoholic steatohepatitis via modulating the miR-21-5p/SFRP5 pathway

Inflammation and oxidative stress are key steps in the progression of non-alcoholic steatohepatitis (NASH). Intervention in these two processes will therefore benefit NASH treatment. Peroxisome proliferator-activated receptor γ (PPARγ), as a multiple functional transcription factor, has been reporte...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Xiying, Deng, Fang, Zhang, Yuping, Zhang, Xiaohong, Chen, Jianfei, Jiang, Youzhao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8485121/
https://www.ncbi.nlm.nih.gov/pubmed/34558644
http://dx.doi.org/10.3892/mmr.2021.12463