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Loss of Wip1 aggravates brain injury after ischaemia/reperfusion by overactivating microglia

BACKGROUND AND PURPOSE: The inflammatory response mediated by microglia/macrophages is closely related to cerebral ischaemia/reperfusion injury. Wild-type p53-induced protein phosphatase 1 (Wip1), a serine/threonine phosphatase, is expressed in various tissues. A growing number of reports have sugge...

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Detalles Bibliográficos
Autores principales: Yan, Feng, Cheng, Xiang, Zhao, Ming, Gong, Shenghui, Han, Ying, Ding, Liping, Wu, Di, Luo, Yumin, Zuo, Wei, Zhu, Lingling, Fan, Ming, Ji, Xunming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8485234/
https://www.ncbi.nlm.nih.gov/pubmed/33452162
http://dx.doi.org/10.1136/svn-2020-000490