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Loss of Wip1 aggravates brain injury after ischaemia/reperfusion by overactivating microglia
BACKGROUND AND PURPOSE: The inflammatory response mediated by microglia/macrophages is closely related to cerebral ischaemia/reperfusion injury. Wild-type p53-induced protein phosphatase 1 (Wip1), a serine/threonine phosphatase, is expressed in various tissues. A growing number of reports have sugge...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8485234/ https://www.ncbi.nlm.nih.gov/pubmed/33452162 http://dx.doi.org/10.1136/svn-2020-000490 |