Cargando…

Loss of Wip1 aggravates brain injury after ischaemia/reperfusion by overactivating microglia

BACKGROUND AND PURPOSE: The inflammatory response mediated by microglia/macrophages is closely related to cerebral ischaemia/reperfusion injury. Wild-type p53-induced protein phosphatase 1 (Wip1), a serine/threonine phosphatase, is expressed in various tissues. A growing number of reports have sugge...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yan, Feng, Cheng, Xiang, Zhao, Ming, Gong, Shenghui, Han, Ying, Ding, Liping, Wu, Di, Luo, Yumin, Zuo, Wei, Zhu, Lingling, Fan, Ming, Ji, Xunming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8485234/ https://www.ncbi.nlm.nih.gov/pubmed/33452162 http://dx.doi.org/10.1136/svn-2020-000490

Ejemplares similares

Interleukin‐7 aggravates myocardial ischaemia/reperfusion injury by regulating macrophage infiltration and polarization
por: Yan, Mengwen, et al.
Publicado: (2021)

Homocysteine Aggravates Cortical Neural Cell Injury through Neuronal Autophagy Overactivation following Rat Cerebral Ischemia-Reperfusion
por: Zhao, Yaqian, et al.
Publicado: (2016)

mTOR Overactivation in Mesenchymal cells Aggravates CCl(4)− Induced liver Fibrosis
por: Shan, Lanlan, et al.
Publicado: (2016)

Overactivated sonic hedgehog signaling aggravates intrauterine adhesion via inhibiting autophagy in endometrial stromal cells
por: Wei, Cheng, et al.
Publicado: (2020)

Correction: Overactivated sonic hedgehog signaling aggravates intrauterine adhesion via inhibiting autophagy in endometrial stromal cells
por: Wei, Cheng, et al.
Publicado: (2020)

Sodium hydrosulfide attenuates cerebral ischemia/reperfusion injury by suppressing overactivated autophagy in rats
por: Jiang, Wen‐Wu, et al.
Publicado: (2017)

Homocysteine exaggerates microglia activation and neuroinflammation through microglia localized STAT3 overactivation following ischemic stroke
por: Chen, Shuang, et al.
Publicado: (2017)

Acute hyperglycaemia enhances oxidative stress and aggravates myocardial ischaemia/reperfusion injury: role of thioredoxin-interacting protein
por: Su, Hui, et al.
Publicado: (2013)

Effects of Cordycepin on the Microglia-Overactivation-Induced Impairments of Growth and Development of Hippocampal Cultured Neurons
por: Peng, Jie, et al.
Publicado: (2015)

Social Isolation Induces Neuroinflammation And Microglia Overactivation, While Dihydromyricetin Prevents And Improves Them
por: Al Omran, Alzahra J, et al.
Publicado: (2021)

Social isolation induces neuroinflammation and microglia overactivation, while dihydromyricetin prevents and improves them
por: Al Omran, Alzahra J., et al.
Publicado: (2022)

Transient Receptor Potential Vanilloid 4 Channel Deficiency Aggravates Tubular Damage after Acute Renal Ischaemia Reperfusion
por: Mannaa, Marwan, et al.
Publicado: (2018)

Necroptosis is a key mediator of enterocytes loss in intestinal ischaemia/reperfusion injury
por: Wen, Shihong, et al.
Publicado: (2016)

Highly pathogenic coronavirus N protein aggravates inflammation by MASP-2-mediated lectin complement pathway overactivation
por: Gao, Ting, et al.
Publicado: (2022)

Necroptosis in Hepatosteatotic Ischaemia-Reperfusion Injury
por: Baidya, Raji, et al.
Publicado: (2020)

Complement in ischaemia–reperfusion injury and transplantation
por: Howard, Mark C., et al.
Publicado: (2021)

Inhibition of microglia overactivation restores neuronal survival in a mouse model of CDKL5 deficiency disorder
por: Galvani, Giuseppe, et al.
Publicado: (2021)

WIP Remodeling Actin behind the Scenes: How WIP Reshapes Immune and Other Functions
por: Noy, Elad, et al.
Publicado: (2012)

Diabetes aggravates myocardial ischaemia reperfusion injury via activating Nox2‐related programmed cell death in an AMPK‐dependent manner
por: Wang, Chunyan, et al.
Publicado: (2020)

Cyclooxygenase‑2 contributes to the hypoxia‑induced aggravation of the neuroinflammation response stimulated by lipopolysaccharide in microglia
por: Yang, Yifan, et al.
Publicado: (2023)

Mitochondrial mechanisms and therapeutics in ischaemia reperfusion injury
por: Martin, Jack L., et al.
Publicado: (2018)

Correction to: Complement in ischaemia–reperfusion injury and transplantation
por: Howard, Mark C., et al.
Publicado: (2022)

TRIM45 causes neuronal damage by aggravating microglia-mediated neuroinflammation upon cerebral ischemia and reperfusion injury
por: Xia, Qian, et al.
Publicado: (2022)

Chlorogenic acid promotes angiogenesis and attenuates apoptosis following cerebral ischaemia-reperfusion injury by regulating the PI3K-Akt signalling
por: Fan, Yong, et al.
Publicado: (2022)

Wip1-dependent modulation of macrophage migration and phagocytosis
por: Tang, Yiting, et al.
Publicado: (2017)

WIP1 and senescence: Oxygen matters
por: Olcina, Monica M, et al.
Publicado: (2014)

The cardioprotective potential of valsartan in myocardial ischaemia reperfusion injury
por: Hadi, Najah R., et al.
Publicado: (2015)

Corticomedullary shunting after ischaemia and reperfusion in the porcine kidney?
por: Rehling, Michael, et al.
Publicado: (2022)

The effects of ischaemic conditioning on lung ischaemia–reperfusion injury
por: Vlastos, Dimitrios, et al.
Publicado: (2022)

Protective effects of remote ischemic preconditioning in rat hindlimb on ischemia- reperfusion injury★
por: Zhang, Ying, et al.
Publicado: (2012)

TRAF1 is a critical regulator of cerebral ischaemia–reperfusion injury and neuronal death
por: Lu, Yan-Yun, et al.
Publicado: (2013)

Severe thiamine deficiency complicated by weight loss protects against renal ischaemia-reperfusion injury in rats
por: Klooster, Astrid, et al.
Publicado: (2009)

Hederagenin Attenuates Cerebral Ischaemia/Reperfusion Injury by Regulating MLK3 Signalling
por: Yu, Hailong, et al.
Publicado: (2020)

Ischaemia-reperfusion injury in photodynamic therapy-treated mouse tumours
por: Korbelik, M, et al.
Publicado: (2003)

A new model for evaluation of thrombosis and ischaemia/reperfusion injury
por: Ravn, HB, et al.
Publicado: (1998)

Effect of pomiferin administration on kidney ischaemia-reperfusion injury in rats
por: Bartošíková, Lenka, et al.
Publicado: (2010)

Pathophysiology of early ischaemia reperfusion injury of the colon in aortic surgery
por: Khwaja, N, et al.
Publicado: (2004)

Which pathways trigger the role of complement in ischaemia/reperfusion injury?
por: Farrar, Conrad A., et al.
Publicado: (2012)

Systemic inflammation affects reperfusion following transient cerebral ischaemia
por: Burrows, F., et al.
Publicado: (2016)

Roles of mitochondrial dynamics modulators in cardiac ischaemia/reperfusion injury
por: Maneechote, Chayodom, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_2lrp4mphsigt8kvkc00jq9q3q2