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Penetrating the Blood-Brain Barrier with New Peptide–Porphyrin Conjugates Having anti-HIV Activity

[Image: see text] Passing through the blood-brain barrier (BBB) to treat neurological conditions is one of the main hurdles in modern medicine. Many drugs with promising in vitro profiles become ineffective in vivo due to BBB restrictive permeability. In particular, this includes drugs such as antiv...

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Detalles Bibliográficos
Autores principales: Mendonça, Diogo A., Bakker, Mariët, Cruz-Oliveira, Christine, Neves, Vera, Jiménez, Maria Angeles, Defaus, Sira, Cavaco, Marco, Veiga, Ana Salomé, Cadima-Couto, Iris, Castanho, Miguel A. R. B., Andreu, David, Todorovski, Toni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8485325/
https://www.ncbi.nlm.nih.gov/pubmed/34033716
http://dx.doi.org/10.1021/acs.bioconjchem.1c00123