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Penetrating the Blood-Brain Barrier with New Peptide–Porphyrin Conjugates Having anti-HIV Activity
[Image: see text] Passing through the blood-brain barrier (BBB) to treat neurological conditions is one of the main hurdles in modern medicine. Many drugs with promising in vitro profiles become ineffective in vivo due to BBB restrictive permeability. In particular, this includes drugs such as antiv...
Autores principales: | Mendonça, Diogo A., Bakker, Mariët, Cruz-Oliveira, Christine, Neves, Vera, Jiménez, Maria Angeles, Defaus, Sira, Cavaco, Marco, Veiga, Ana Salomé, Cadima-Couto, Iris, Castanho, Miguel A. R. B., Andreu, David, Todorovski, Toni |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2021
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8485325/ https://www.ncbi.nlm.nih.gov/pubmed/34033716 http://dx.doi.org/10.1021/acs.bioconjchem.1c00123 |
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