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Fetal hemoglobin rescues ineffective erythropoiesis in sickle cell disease

While ineffective erythropoiesis has long been recognized as a key contributor to anemia in thalassemia, its role in anemia of sickle cell disease (SCD) has not been critically explored. Using in vitro and in vivo derived human erythroblasts we assessed the extent of ineffective erythropoiesis in SC...

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Detalles Bibliográficos
Autores principales: El Hoss, Sara, Cochet, Sylvie, Godard, Auria, Yan, Hongxia, Dussiot, Michaël, Frati, Giacomo, Boutonnat-Faucher, Bénédicte, Laurance, Sandrine, Renaud, Olivier, Joseph, Laure, Miccio, Annarita, Brousse, Valentine, Mohandas, Narla, El Nemer, Wassim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8485663/
https://www.ncbi.nlm.nih.gov/pubmed/32855279
http://dx.doi.org/10.3324/haematol.2020.265462