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Fetal hemoglobin rescues ineffective erythropoiesis in sickle cell disease
While ineffective erythropoiesis has long been recognized as a key contributor to anemia in thalassemia, its role in anemia of sickle cell disease (SCD) has not been critically explored. Using in vitro and in vivo derived human erythroblasts we assessed the extent of ineffective erythropoiesis in SC...
Autores principales: | El Hoss, Sara, Cochet, Sylvie, Godard, Auria, Yan, Hongxia, Dussiot, Michaël, Frati, Giacomo, Boutonnat-Faucher, Bénédicte, Laurance, Sandrine, Renaud, Olivier, Joseph, Laure, Miccio, Annarita, Brousse, Valentine, Mohandas, Narla, El Nemer, Wassim |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Fondazione Ferrata Storti
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8485663/ https://www.ncbi.nlm.nih.gov/pubmed/32855279 http://dx.doi.org/10.3324/haematol.2020.265462 |
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