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Protein-L-isoaspartate O-methyltransferase is required for in vivo control of oxidative damage in red blood cells

Red blood cells (RBC) have the special challenge of a large amount of reactive oxygen species (from their substantial iron load and Fenton reactions) combined with the inability to synthesize new gene products. Considerable progress has been made in elucidating the multiple pathways by which RBC neu...

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Detalles Bibliográficos
Autores principales: D’Alessandro, Angelo, Hay, Ariel, Dzieciatkowska, Monika, Brown, Benjamin C., Morrison, Evan J, Hansen, Kirk C., Zimring, James C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8485689/
https://www.ncbi.nlm.nih.gov/pubmed/33054131
http://dx.doi.org/10.3324/haematol.2020.266676