Chronic lymphocytic leukemia cells impair osteoblastogenesis and promote osteoclastogenesis: role of TNFα, IL-6 and IL-11 cytokines

Bone skeletal alterations are no longer considered a rare event in chronic lymphocytic leukemia (CLL), especially at more advanced stages of the disease. This study is aimed at elucidating the mechanisms underlying this phenomenon. Bone marrow stromal cells, induced to differentiate toward osteoblas...

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Detalles Bibliográficos
Autores principales: Giannoni, Paolo, Marini, Cecilia, Cutrona, Giovanna, Matis, Serena, Capra, Maria Cristina, Puglisi, Francesca, Luzzi, Paola, Pigozzi, Simona, Gaggero, Gabriele, Neri, Antonino, Todoerti, Katia, Morabito, Fortunato, Ibatici, Adalberto, Miglino, Maurizio, Bergamaschi, Micaela, Bruno, Silvia, Sambuceti, Gian Mario, Ravetti, Jean Louis, Ferrarini, Manlio, Fais, Franco, de Totero, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8485691/
https://www.ncbi.nlm.nih.gov/pubmed/32855274
http://dx.doi.org/10.3324/haematol.2019.231456

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8485691/
https://www.ncbi.nlm.nih.gov/pubmed/32855274
http://dx.doi.org/10.3324/haematol.2019.231456

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