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Elucidating the Binding Mode between Heparin and Inflammatory Cytokines by Molecular Modeling

Heparan sulfate (HS) interacts with a broad spectrum of inflammatory cytokines, thereby modulating their biological activities. It is believed that there is a structural‐functional correlation between each protein and sugar sequences in the HS polysaccharides, however, the information in this regard...

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Detalles Bibliográficos
Autores principales: Yu, Mingjia, Zhang, Tianji, Li, Jin‐ping, Tan, Yingxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8485826/
https://www.ncbi.nlm.nih.gov/pubmed/34596979
http://dx.doi.org/10.1002/open.202100135