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Evaluation of 3‐ and 4‐Phenoxybenzamides as Selective Inhibitors of the Mono‐ADP‐Ribosyltransferase PARP10

Intracellular ADP‐ribosyltransferases catalyze mono‐ and poly‐ADP‐ribosylation and affect a broad range of biological processes. The mono‐ADP‐ribosyltransferase PARP10 is involved in signaling and DNA repair. Previous studies identified OUL35 as a selective, cell permeable inhibitor of PARP10. We ha...

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Detalles Bibliográficos
Autores principales: Korn, Patricia, Classen, Arno, Murthy, Sudarshan, Guareschi, Riccardo, Maksimainen, Mirko M., Lippok, Barbara E., Galera‐Prat, Albert, Sowa, Sven T., Voigt, Catharina, Rossetti, Giulia, Lehtiö, Lari, Bolm, Carsten, Lüscher, Bernhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8485830/
https://www.ncbi.nlm.nih.gov/pubmed/34145784
http://dx.doi.org/10.1002/open.202100087