Inhibition of Drug‐Induced Liver Injury in Mice Using a Positively Charged Peptide That Binds DNA

Hepatic cell death occurs in response to diverse stimuli such as chemical and physical damage. The exposure of intracellular contents such as DNA during necrosis induces a severe inflammatory response that has yet to be fully explored therapeutically. Here, we sought means to neutralize the ability...

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Detalles Bibliográficos
Autores principales: Marques, Pedro E., Vandendriessche, Sofie, de Oliveira, Thiago H.C., Crijns, Helena, Lopes, Mateus E., Blanter, Marfa, Schuermans, Sara, Yu, Karen, Poosti, Fariba, Vanheule, Vincent, Janssens, Rik, Boff, Daiane, Kungl, Andreas J., Menezes, Gustavo B., Teixeira, Mauro M., Proost, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8485890/
https://www.ncbi.nlm.nih.gov/pubmed/34532999
http://dx.doi.org/10.1002/hep4.1759

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8485890/
https://www.ncbi.nlm.nih.gov/pubmed/34532999
http://dx.doi.org/10.1002/hep4.1759

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